Viral infections evidence library
Influenza
A living PubMed evidence library for human influenza prevention, antiviral treatment, vaccines, severe disease, resistance, and emerging strains.
Living evidence synopsis
What the current PubMed collection shows.
Alexandria currently organizes 0 non-retracted PubMed-indexed records for Influenza. The structured collection includes 0 guideline or consensus records, 0 evidence syntheses/systematic reviews/meta-analyses, and 0 randomized or phase III studies. 0 records were identified by the configured last-24-month search. Conflict-of-interest statements are available in the PubMed record for 0 of 0 included records.
Research landscape
Charts are generated from Alexandria’s structured PubMed records, not copied from journal figures.
Records by publication year
Study designs
Conflict-of-interest reporting
Absence of a conflict-of-interest statement in PubMed does not establish that no conflict existed.
Extracted result direction
Funding and conflicts of interest
Conflict and funding fields reproduce what is available in PubMed records. Missing disclosure data does not establish that no conflict or funding existed.
No funding agency was identified in the retrieved PubMed records.
Current Standard-of-Care Sources
Alexandria uses this label only for PubMed-indexed guidelines or consensus documents. These are source publications, not individualized recommendations.
No eligible guideline has been indexed in this snapshot.
The absence of a result is shown rather than filled from outside knowledge.
Highest-Priority Research
High-priority evidence has not been processed yet.
Latest Research — Last 24 Months
No recent records have been processed yet.
Treatment Options Studied in the PubMed Collection
These are interventions detected in PubMed metadata and abstracts. Inclusion does not establish approval, effectiveness, suitability, or standard-of-care status.
Structured treatment extraction has not completed yet.
The background evidence pipeline will populate this section after PubMed retrieval and extraction.
Conflicting Research
No directly conflicting cluster has been identified yet.
This can mean the evidence is consistent, insufficient, or not detailed enough in the available abstracts to compare.
Failed or Negative Trials
No trial with a directly extractable failed/null primary finding has been processed yet.
Emerging and Experimental Research
No early-phase or preclinical record has been processed yet.
Evidence Gaps
No randomized or phase III evidence identified
The current PubMed collection does not contain a classified randomized or phase III study for this topic.
No PubMed-indexed guideline identified
Alexandria did not identify a guideline or consensus publication in the configured searches.
Complete Ranked PubMed Index
The retrieval-priority score orders records using publication type, recency, sample-size signals, and replication signals. It is not a recommendation or a formal risk-of-bias grade.
Current Standard Of Care10 records
Recommendations for Prevention and Control of Influenza in Children, 2024-2025: Policy Statement.
Pediatrics · 2024 · PMID 39183669
This statement updates the recommendations of the American Academy of Pediatrics for the routine use of influenza vaccines and antiviral medications in the prevention and treatment of influenza in children during the 2024-2025 influenza season. A detailed review of the evidence supporting these recommendations is published in the accompanying technical report (www.pediatrics.org/cgi/doi/10.1542/peds.2024-068508). The American Academy of Pediatrics recommends annual influenza vaccination of all children without medi…
Recommendations for Prevention and Control of Influenza in Children, 2024-2025: Technical Report.
Pediatrics · 2024 · PMID 39183667
This technical report accompanies the recommendations of the American Academy of Pediatrics for the routine use of influenza vaccine and antiviral medications in the prevention and treatment of influenza in children during the 2024 to 2025 season. The rationale for the American Academy of Pediatrics recommendation for annual influenza vaccination of all children without medical contraindications starting at 6 months of age is provided. Influenza vaccination is an important strategy for protecting children and the b…
Improving vaccination uptake among adolescents.
The Cochrane database of systematic reviews · 2020 · PMID 31978259
BACKGROUND: Adolescent vaccination has received increased attention since the Global Vaccine Action Plan's call to extend the benefits of immunisation more equitably beyond childhood. In recent years, many programmes have been launched to increase the uptake of different vaccines in adolescent populations; however, vaccination coverage among adolescents remains suboptimal. Therefore, understanding and evaluating the various interventions that can be used to improve adolescent vaccination is crucial. OBJECTIVES: To …
Healthcare system disruption across WHO-declared PHEICs: a 4S comparative case analysis.
Frontiers in public health · 2026 · PMID 42807059
OBJECTIVES: To compare documented patterns of healthcare-system disruption and response across WHO-declared Public Health Emergencies of International Concern (PHEICs) using the established 4S surge-capacity framework (Staff, Stuff, Space, Systems) and an author-developed 12-indicator operationalization. METHODS: We conducted a structured comparative case analysis, not a systematic review of intervention effects, of all eight PHEIC events declared by WHO through 31 March 2026. The unit of analysis was the event, an…
Postural Orthostatic Tachycardia Syndrome (POTS): A Review.
JAMA · 2026 · PMID 42635998
IMPORTANCE: Postural orthostatic tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by excessive orthostatic tachycardia and multisystem symptoms that affects an estimated 0.1% to 1% of the US population. POTS can substantially impair daily functioning and quality of life. OBSERVATIONS: Consensus criteria define POTS by chronic symptoms of orthostatic intolerance accompanied by a sustained heart rate increase of at least 30 beats/min (≥40 beats/min in adolescents aged 12-19 years) within 10 m…
[Influenza vaccination as an intervention for cardiovascular prevention and protection in high-risk patients. SIPREC/ANMCO/SIMI/FADOI/ARCA consensus document].
Giornale italiano di cardiologia (2006) · 2026 · PMID 42788302
Influenza infection is associated with an increase of cardiovascular events and hospitalizations due to cardiovascular disease. Influenza vaccination is in turn associated with a reduction or mitigation of cardiovascular complications of influenza. For this reason, influenza vaccination represents an additional pillar for cardiovascular prevention and protection. Recent randomized studies conducted in a very large European population have shown that high-dose influenza vaccination provides significant advantages wh…
What do those who vaccinate think? Perception of the flu among pediatrician and pediatric nursing professionals.
Anales de pediatria · 2026 · PMID 42668227
INTRODUCTION: Childhood influenza represents a significant healthcare burden, in terms of both primary care and hospital emergency department visits, as well as in hospitalizations. The objective of this study was to analyze the perceptions of pediatricians and nurses working in pediatric settings regarding childhood influenza and influenza vaccination, as well as the perceived barriers, in order to identify new strategies to improve vaccination coverage. MATERIALS AND METHODS: Cross-sectional, observational, and d…
Consensus based expert recommendations for management and prevention of RSV infections in older adults in emerging market countries: results from an expert panel structured survey.
Expert review of vaccines · 2026 · PMID 42596759
BACKGROUND: Respiratory syncytial virus (RSV) can cause serious disease in older adults (OAs), particularly those with comorbidities. It is a leading cause of acute respiratory illness and lower respiratory tract infections in adults ≥60 years. Its impact on morbidity, mortality, and healthcare systems is becoming evident. Questions about the burden of disease (BoD) are raised due to underdiagnosis and the similarity with other respiratory illnesses. First opportunities for prevention came in 2023 and 2024, with va…
[Comprehensive cardiovascular prevention: the role of vaccination in older adults with cardiovascular disease. Expert consensus document].
Semergen · 2026 · PMID 42508371
INTRODUCTION: Respiratory and systemic infections can trigger cardiovascular events by increasing inflammation, atherosclerotic plaque instability, and a prothrombotic state. Given this situation, vaccination is a relevant preventive tool in patients with cardiovascular disease (CVD). OBJECTIVE: To review the available evidence on the impact of vaccination in patients with CVD and to propose recommendations to improve vaccination coverage in clinical practice. CONTENT: This expert consensus, developed through a str…
Guided design for the development of an evolution-proof influenza vaccine.
Vaccine · 2025 · PMID 40398325
Influenza remains a significant public health concern, particularly among high-risk populations, due to its capacity to cause annual epidemics and potentially trigger global pandemics. Despite the availability of countermeasures such as vaccines and antiviral treatments, their effectiveness is hindered by factors such as resistance development with manufacturing of the influenza vaccine still heavily relying on decades-old technologies. This review therefore examines the mechanisms by which influenza viruses evade …
Alexandria organizes PubMed-indexed literature. PubMed inclusion does not establish accuracy, endorsement, clinical applicability, or treatment suitability. Automated extraction can contain errors or omissions. This page is not medical advice.